1.
An. bras. dermatol
;
97(1): 112-115, Jan.-Feb. 2022. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-1360074
2.
An. bras. dermatol
;
97(1): 63-74, Jan.-Feb. 2022. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-1360091
RESUMEN
Abstract Generalized pustular psoriasis (von Zumbusch) is a rare and acute eruption characterized by multiple sterile pustules over an erythematous and edematous background, eventually associated with psoriasis vulgaris. Classically, it manifests as a potentially severe systemic picture and demands prompt diagnosis and intervention. The duration of each flare-up and intervals between the pustular episodes is extremely variable. Recently, genetic abnormalities have been identified mainly in the familial and early variants of this disease. The therapeutic arsenal is limited; however, new drugs being evaluated aim to control both pustular flare-ups and disease recurrences.